Seinen is a demographic for Japanese manga targeting the teenage and adult market.
The difference between seinen and shonen (aimed at boys of 12-18) is often simply in the sexual situations or violence shown. But there are also themes such as delinquency, coming of age, inequality in society, loneliness (of suburban life), prostitution, etc.”that challenge our normal assumptions about good and bad; high art promises aesthetic pleasure that has sensual meaning” according to one definition on Wikipedia.